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Showing posts from May, 2025

Is coming off semaglutide slowly the key to stop weight regain?

  Semaglutide, marketed under brand names like Ozempic and Wegovy, has revolutionized weight management, offering significant weight loss for many individuals. However, a common concern arises: what happens after discontinuation, and can a gradual reduction in dosage help maintain the achieved weight loss? Understanding Semaglutide's Role in Weight Loss Semaglutide is a GLP-1 receptor agonist that aids in weight loss by mimicking the GLP-1 hormone, which regulates appetite and insulin secretion. Clinical trials have demonstrated that semaglutide can lead to an average weight loss of approximately 15% of body weight when combined with a reduced-calorie diet and increased physical activity. However, weight regain is a significant concern after stopping the medication. The Impact of Gradual Discontinuation While research on the effects of tapering off semaglutide is limited, some experts suggest that a gradual reduction in dosage may help mitigate potential weight regain. Dr. Henrik...

The Long-Term Weight Loss Effects of Semaglutide in People with Obesity but No Diabetes

  In recent years, semaglutide has emerged as one of the most promising medications in the fight against obesity. Originally developed to treat type 2 diabetes, semaglutide has since gained attention—and regulatory approval—for its potent weight loss effects, even in individuals without diabetes. But how effective is semaglutide in the long run? And is it a sustainable option for weight management in people with obesity but no diabetes? Let’s dive into what the science says and explore how semaglutide could reshape the future of weight loss treatment. What is Semaglutide? Semaglutide is a medication that mimics a naturally occurring hormone in the body called glucagon-like peptide-1 (GLP-1). This hormone plays a crucial role in regulating appetite, food intake, and blood sugar levels. By activating GLP-1 receptors, semaglutide helps people feel fuller sooner and reduces hunger between meals. Initially prescribed for managing type 2 diabetes (marketed as Ozempic), semaglutide was ...