Semaglutide, marketed under brand names like Ozempic and Wegovy, has revolutionized weight management, offering significant weight loss for many individuals. However, a common concern arises: what happens after discontinuation, and can a gradual reduction in dosage help maintain the achieved weight loss? Understanding Semaglutide's Role in Weight Loss Semaglutide is a GLP-1 receptor agonist that aids in weight loss by mimicking the GLP-1 hormone, which regulates appetite and insulin secretion. Clinical trials have demonstrated that semaglutide can lead to an average weight loss of approximately 15% of body weight when combined with a reduced-calorie diet and increased physical activity. However, weight regain is a significant concern after stopping the medication. The Impact of Gradual Discontinuation While research on the effects of tapering off semaglutide is limited, some experts suggest that a gradual reduction in dosage may help mitigate potential weight regain. Dr. Henrik...
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